Variations in systemic biomarkers of oxidative/nitrosative stress and DNA damage before and during the consequent two cycles of chemotherapy in breast cancer patients

Atukeren P., Yavuz B., Soydinc H. O., Purisa S., Camlica H., Gumustas M. K., ...Daha Fazla

CLINICAL CHEMISTRY AND LABORATORY MEDICINE, cilt.48, sa.10, ss.1487-1495, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 10
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1515/cclm.2010.249
  • Dergi Adı: CLINICAL CHEMISTRY AND LABORATORY MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1487-1495
  • Anahtar Kelimeler: 8-hydroxydeoxyguanosine, breast cancer, chemotherapy, nitrosative stress, oxidative stress, CELL LUNG-CANCER, LIPID-PEROXIDATION, ANTIOXIDANT STATUS, OXIDATIVE STRESS, NITRIC-OXIDE, BLOOD, TUMOR, ANTHRACYCLINE, ADRIAMYCIN, CAPACITY
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background: Previous studies have suggested the importance of redox regulation in carcinogenesis. The aim of this study was to evaluate the prognostic role of altered redox homeostasis and oxidative DNA damage in patients with breast carcinoma before and during two cycles of chemotherapy.