Is there additional effect of MTHFR C677T mutation on lipid abnormalities in renal allograft recipients?

YILMAZ H., Agachan B., ISBIR T., AKOGLU E.

TRANSPLANTATION PROCEEDINGS, cilt.35, sa.4, ss.1390-1392, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 4
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1016/s0041-1345(03)00454-8
  • Dergi Adı: TRANSPLANTATION PROCEEDINGS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1390-1392
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background. The MTHFR C677T mutation and elevated atherogenic lipoprotein levels are known as cardiovascular risk factors in patients with renal transplantation treated with cyclosporine (CsA). The aim of the present study was to evaluate the contribution of MTHFR C677T mutation to the risk of dyslipidemia in renal transplant recipients. We also studied the effect of the MTHFR-C677 T genotype on transplant survival.