Impact of Nonosseous Findings on F-18-NaF PET/CT in a Patient with Ductal Breast Carcinoma


Kuyumcu S., Adalet I., Isik E. G., Unal S.

NUCLEAR MEDICINE AND MOLECULAR IMAGING, vol.48, no.1, pp.72-74, 2014 (ESCI, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 1
  • Publication Date: 2014
  • Doi Number: 10.1007/s13139-013-0235-3
  • Journal Name: NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Page Numbers: pp.72-74
  • Keywords: F-18-NaF PET/CT, F-18-FDG PET/CT, Bone metastasis, Breast carcinoma, F-18-FLUORIDE, METASTASES
  • Istanbul University Affiliated: Yes

Abstract

F-18-NaF was used as a bone-seeking PET tracer for skeletal imaging until the introduction of the widely available Tc-99m-labeled bone agents. However, there is renewed clinical interest in F-18-NaF since prior technical and logistic limitations to its routine use are no longer present, and, as a consequence, it is likely that uptake unrelated to bone and non-osseous findings will be encountered more frequently. As a result of tumoral necrosis, soft tissue metastases may demonstrate F-18-NaF avidity due to dystrophic calcification. On the other hand, all non-osseous findings, whether F-18-NaF avid or not, may provide important diagnostic information that may alter the course of the disease, including treatment options. Herein we present a patient with ductal carcinoma of the breast in whom findings unrelated to the skeletal system in F-18-NaF PET/CT altered the treatment strategy.