Dopamine D4 Receptor Gene Exon III VNTR Variant Influences Smoking Status in Turkish Population

Uysal M. A., Sever U., NURSAL A. F., Pehlivan S., Bahadir A., Yurt S., ...Daha Fazla

NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, cilt.56, sa.4, ss.248-252, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 56 Sayı: 4
  • Basım Tarihi: 2019
  • Doi Numarası: 10.29399/npa.23408
  • Dergi Adı: NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.248-252
  • Anahtar Kelimeler: Smoking, Dopamine D4 receptor, gene, variant, POLYMORPHISM, NEUROBIOLOGY
  • İstanbul Üniversitesi Adresli: Evet

Özet

Introduction: Dopaminergic gene variants may affect nicotine dependence through their possible impact on the dopamine reward pathway. The purpose of this study is to investigate the relationship between the variable number tandem repeat (VNTR) variant in exon III of the Dopamine D4 receptor (DRD4) gene and genetic predisposition of smoking status in a Turkish population.