Parathyroid Hormone(PTH) in Oral Surgery: A case report and literature review

Koltuk M. , Çankaya A. B. , Gürkan Köseoğlu B. , Bahtiyar İ.

25th International Scientific Congress of Turkish Association of Oral and Maxillofacial Surgery , Girne, Cyprus (Kktc), 13 - 17 May 2018, pp.137-138

  • Publication Type: Conference Paper / Summary Text
  • City: Girne
  • Country: Cyprus (Kktc)
  • Page Numbers: pp.137-138


Objective: Primer hyperparathyroidism (PHPT) is defined as a condition of hypercalcemia

due to parathyroid glands’ hyperfunction. PHPT cases are caused by 80% to 85% of Parathyroid

adenomas and 1% of parathyroid malignency. Despite being a most important sign

of hyperparatiroidism, PTH can also use for treatment. PTH can be used in oral surgery for

treatment of MRONJ(Medication Related Osteonecrosis of Jaw), osteoradionecrosis defects

and brown tumor, and also to enhance consolidation phase of distraction osteogenesis.

Case: In following case patient referred our clinic with complaint of mandibular pain, and

after radiographic evaluation bilateral multilocular radiolucent lesions was noticed. Because

of bilateral involvement, patient looked for a systemic problem such as primer hyperparathyroidism

so before incisional biopsy, patient was advised blood investigations that revealed

PTH level of 784 IU/L. Patient immediately directed to endocrinology. As a consequence of

other blood and radiographic investigations, patient diagnosed Hurthle Cell Follicular Carcinoma

and thyroidectomy operation was done by endocrinology department.

Conclusion: Evaluation of radiolucent lesions on jaws may act a significant part of detecting

endocrine malignancies. Oral surgeons’ role in this issue is quite important and crucial for

early diagnosis.