Flavonoids of Helichrysum chasmolycicum and its antioxidant and antimicrobial activities

Suzgec-Selcuk S., Birteksoz A. S.

SOUTH AFRICAN JOURNAL OF BOTANY, cilt.77, sa.1, ss.170-174, 2011 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 77 Sayı: 1
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.sajb.2010.07.017
  • Dergi Adı: SOUTH AFRICAN JOURNAL OF BOTANY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.170-174
  • Anahtar Kelimeler: Flavonoids, Antioxidant ativity, Antimicrobial activity, Helichrysum chasmolycicum, 3,5-dihydroxy-6,7,8-trimethoxyflavone, MEDICINAL-PLANTS, ESSENTIAL OIL, CONSTITUENTS, ZULU
  • İstanbul Üniversitesi Adresli: Evet

Özet

From the aerial parts of Helichrysum chasmolycicum P.H Davis, which is an endemic species in Turkey, the flavonoids apigenin, luteolin, kaempferol, 3,5-dihydroxy-6,7,8-trimethoxyflavone, 3,5-dihydroxy-6,7,8,4'-tetramethoxyflavone, apigenin 7-O-glucoside, apigenin 4'-O-glucoside, luteolin 4'-O-glucoside, luteolin 4',7-O-diglucoside, kaempferol 3-O-glucoside, kaempferol 7-O-glucoside and quercetin 3-O-glucoside were isolated. The methanol extract of the aerial parts of H. chasmolycicum showed antioxidant activity by DPPH method (10(50) 0.92 mg/mL). Antimicrobial activity test was performed on the B, D, E extracts and also 3,5-dihydroxy-6,7,8-trimethoxyflavone and kaempferol 3-O-glucoside which were the major flavonoid compounds obtained from aerial parts of H. chasmolycicum by microbroth dilutions technique. The E (ethanol-ethyl acetate) extract showed moderate antimicrobial activity against Pseudomonas aeruginosa, B (petroleum ether-60% ethanol-chloroform) extract and 3,5-dihydroxy-6,7,8-trimethoxyflavone showed moderate antifungal activity against Candida albicans. (C) 2010 SAAB. Published by Elsevier B.V. All rights reserved.