Determining the cut-off values of tumor diameter, degree of extraprostatic extension, and extent of surgical margin positivity with regard to biochemical recurrence of prostate cancer after radical prostatectomy

Kir, Gozde; Arikan, Evşen; Seneldir, Hatice; ANKARALI, HANDAN; Oznergiz, Seca; Olgun, Zeynep; Yildirim, Asif

doi:10.1016/j.anndiagpath.2019.151431

Determining the cut-off values of tumor diameter, degree of extraprostatic extension, and extent of surgical margin positivity with regard to biochemical recurrence of prostate cancer after radical prostatectomy

Atıf İçin Kopyala

Kir G., Arikan E., Seneldir H., ANKARALI H., Oznergiz S., Olgun Z. C., ...Daha Fazla

ANNALS OF DIAGNOSTIC PATHOLOGY, cilt.44, 2020 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 44
Basım Tarihi: 2020
Doi Numarası: 10.1016/j.anndiagpath.2019.151431
Dergi Adı: ANNALS OF DIAGNOSTIC PATHOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
İstanbul Üniversitesi Adresli: Evet

Özet

Background: The pre-biopsy (bx) prostate-specific antigen (PSA) level, tumor volume/diameter, degree of extraprostatic extension (EPE), and extent of surgical margin positivity have been shown to be significant prognostic parameters of biochemical recurrence (BCR) after radical prostatectomy. The present study assessed the cut-off values of the pre-bx PSA level, maximum tumor diameter, radial and circumferential distances of EPE, and circumferential length of surgical margin (SM) positivity with regard to BCR.