Possible relationship between the resistin gene C-420G polymorphism and colorectal cancer in a Turkish population

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Düzköylü Y., Arıkan S., Turan S., Yaylim I., Doğan M. B., Sarı S., ...Daha Fazla

TURKISH JOURNAL OF GASTROENTEROLOGY, cilt.26, sa.5, ss.392-396, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 5
  • Basım Tarihi: 2015
  • Doi Numarası: 10.5152/tjg.2015.0188
  • Dergi Adı: TURKISH JOURNAL OF GASTROENTEROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.392-396
  • Anahtar Kelimeler: Colorectal cancer, gene polymorphism, resistin, INSULIN-RESISTANCE, ADIPOSE-TISSUE, PROMOTER, GENOTYPE, RISK, INFLAMMATION, ASSOCIATION, ADIPONECTIN, EXPRESSION
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background/Aims: In recent years, with improvements in genotyping, a possible relationship between obesity-related gene polymorphisms and colorectal cancer (CRC) has been studied. The promoter region C-420G of the resistin gene is believed to have an important role in the development of malignancy. We prospectively evaluated the possible effect of the resistin C-420G polymorphism on the risk and prognosis of CRC.