Comparison of the distinctive pathological features of and p16 and c-Kit expression levels in benign and malignant endometrial polyps

Koc N., Ayas S., UYGUR L., Ozel Ozbay N.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.46, sa.6, ss.1822-1828, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46 Sayı: 6
  • Basım Tarihi: 2016
  • Doi Numarası: 10.3906/sag-1508-39
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1822-1828
  • Anahtar Kelimeler: p16, c-Kit, endometrial polyp, tubal metaplasia, CD117, ADENOCARCINOMA, TRANSFORMATION, HYPERPLASIA, METAPLASIA, P16(INK4A), CARCINOMA, DIAGNOSIS, TISSUES, CANCER
  • İstanbul Üniversitesi Adresli: Hayır

Özet

Background/aim: Histopathological examination is crucial for the effective management of endometrial polyps. Immunohistochemical markers such as p16 and c-Kit may facilitate the differential diagnoses of benign and malignant polyps. The aim of the present study was to explore the expression levels of c-Kit (CD117) and p16 in endometrial polyps of postmenopausal women.