INTER-POPULATION COMPARISONS AND THE IMPORTANCE IN INFECTIOUS DISEASES OF THE IRF7, TBK1, IFNAR1, IFNAR2 AND TLR3 GENE VARIANTS IN TURKISH INDIVIDUALS
JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI, cilt.85, sa.3, ss.344-354, 2022 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 85 Sayı: 3
- Basım Tarihi: 2022
- Doi Numarası: 10.26650/iuitfd.1060030
- Dergi Adı: JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.344-354
- Anahtar Kelimeler: Infectious diseases, population, immunity genes, variant, MEDICAL GENETICS, AMERICAN-COLLEGE, GENOMICS
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- İstanbul Üniversitesi Adresli: Evet
Özet
Objective: In the research conducted during the pandemic period, it has been determined that IRF7, TBK1, IFNAR1, IFNAR2, and TLR3 immunity genes play an important role in the predisposition to SARS-CoV-2 infection. However, there is no information about variants of these genes in the Turkish population. The aim of this study was to determine the variants specific to the our study's population in these genes that predispose to infections and to compare them with other populations.