"The Role Of Candida Albicans Hyphae And Lactobacillus In Denture Related Stomatitis"


BİLHAN H. , SÜLÜN T. , ERKÖSE G., Kurt H., ERTURAN Z. , KUTAY H. Ö. , ...More

Journal of Clinical Oral Investigations, vol.13, no.4, pp.363-368, 2009 (Journal Indexed in SCI Expanded)

  • Publication Type: Article / Article
  • Volume: 13 Issue: 4
  • Publication Date: 2009
  • Title of Journal : Journal of Clinical Oral Investigations
  • Page Numbers: pp.363-368

Abstract

Denture-related stomatitis (DRS) is still a dilemma in removable prosthodontics.
The aim of this study was to investigate the relationship of DRS with the
presence of Candida albicans hyphae and Lactobacillus. A total of 91 patients
wearing maxillary and mandibular complete dentures were included in the present
study and tested mycologically as well as bacteriologically. A statistically
significant association of DRS was found with denture age (p = 0.003) and
continuous denture wearing (p = 0.015). Presence of C. albicans hyphae was shown
to be significantly higher in DRS cases (p < 0.01), and there was a statistically
significant positive correlation between presence of hyphae and C. albicans (p <
0.01). Another interesting finding was that DRS patients showed higher
Lactobacillus counts in their saliva (p = 0.04), as well as in the palate (p =
0.028). C. albicans is an important factor in the development of DRS. Hyphae seem
to facilitate the rise of C. albicans counts and be related to the inflammatory
response of the tissues. Lactobacillus seems to play an important role in the
presence of DRS, as well. In agreement with many other studies, the results of
this study confirm the importance of denture age and continuous denture wearing
in the development of DRS.