In vitro cytotoxic effect of tyrosine kinase inhibitor sunitinib malate alone and in combination with hyperthermia on breast adenocarcinoma MCF-7 cells

Topcul M. R., Cetin I.

JOURNAL OF BUON, vol.21, no.3, pp.556-563, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 3
  • Publication Date: 2016
  • Journal Name: JOURNAL OF BUON
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.556-563
  • Keywords: breast cancer, cell kinetic, hyperthermia, MCF-7 cells, sunitinib malate, LOCAL HYPERTHERMIA, GROWTH-FACTOR, CANCER, SU11248, CHEMOTHERAPY, RADIOSENSITIZATION, PROLIFERATION, APOPTOSIS, THERAPY, VEGF
  • Istanbul University Affiliated: Yes


Purpose: In this study, the in vitro cytotoxic effect of sunitinib malate alone and combination with hyperthermia was evaluated on MCF-7 cells (human breast adenocarcinoma cell line).