Coexistence of Guillain-Barre syndrome and Behcet's disease

Shugaiv E., Kiyat-Atamer A., Tuzun E., Deymeer F., Oflazer P., Parman Y., ...More

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, vol.31, no.3, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 3
  • Publication Date: 2013
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: Behcet's disease, neuro-Behcet, polyneuropathy, Guillain-Barre syndrome, autoimmunity, NEUROLOGICAL INVOLVEMENT, T-CELLS
  • Istanbul University Affiliated: Yes


Behcet's disease (BD) is a multisystemic, recurrent and inflammatory disorder. Neurological involvement is rare and affects mainly the central nervous system (CNS) in the form of brainstem meningoencephalitis or dural sinus thrombosis. Peripheral neuropathy is usually not observed during the course of BD but some reports have shown electrophysiologic evidence of subclinical neuropathy, mononeuritis multiplex and cranial neuropathy in BD patients. The co-occurrence of Guillain-Barre syndrome (GBS), an acute inflammatory demyelinating neuropathy, with other autoimmune or systemic diseases is rare. We present a case of BD with clinical and electrophysiological diagnosis of GBS. The findings of the patient were discussed with reference to literature.