Gender specific association of ABCA1 gene R219K variant in coronary disease risk through interactions with serum triglyceride elevation in Turkish adults
ANATOLIAN JOURNAL OF CARDIOLOGY, cilt.14, sa.1, ss.18-25, 2014 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 14 Sayı: 1
- Basım Tarihi: 2014
- Doi Numarası: 10.5152/akd.2013.234
- Dergi Adı: ANATOLIAN JOURNAL OF CARDIOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
- Sayfa Sayıları: ss.18-25
- Anahtar Kelimeler: ABCA1 gene variants, coronary heart disease risk, gender difference, phospholipids, serum triglycerides, Turkish population, regression analysis, HIGH-DENSITY-LIPOPROTEIN, CASSETTE TRANSPORTER A1, METABOLIC SYNDROME, CARDIOVASCULAR-DISEASE, CHOLESTEROL LEVELS, LOW HDL, POLYMORPHISM, EFFLUX, DEFINITION, PATHWAYS
- İstanbul Üniversitesi Adresli: Evet
Özet
Objective: ATP binding cassette transporter A1 (ABCA1) controls the reverse cholesterol transport. Some ABCA1 variants are correlated with serum high-density lipoprotein cholesterol (HDL-C) and other lipid concentrations. We aimed to explore the relationship of ABCA1 gene with both the lipid profile and coronary heart disease (CHD) risk.