Clusterin Is a Gene-Specific Target of microRNA-21 in Head and Neck Squamous Cell Carcinoma

Mydlarz, Wojciech; Uemura, Mamoru; Ahn, Sun; Hennessey, Patrick; Chang, Steven; Demokan, Semra; Sun, Wenyue; Shao, Chunbo; Bishop, Justin; Krosting, Julie; Mambo, Elizabeth; Westra, William; Ha, Patrick; Sidransky, David; Califano, Joseph

doi:10.1158/1078-0432.ccr-13-2675

Clusterin Is a Gene-Specific Target of microRNA-21 in Head and Neck Squamous Cell Carcinoma

Mydlarz W., Uemura M., Ahn S., Hennessey P., Chang S., Demokan S., ...More

CLINICAL CANCER RESEARCH, vol.20, no.4, pp.868-877, 2014 (SCI-Expanded)

Publication Type: Article / Article
Volume: 20 Issue: 4
Publication Date: 2014
Doi Number: 10.1158/1078-0432.ccr-13-2675
Journal Name: CLINICAL CANCER RESEARCH
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
Page Numbers: pp.868-877
Istanbul University Affiliated: Yes

Abstract

Purpose: MicroRNA-21 (miRNA-21) has proto-oncogenic properties, although no miRNA-21-specific targets have been found in head and neck squamous cell carcinoma (HNSCC). Further study of miRNA-21 and its specific targets is essential to understanding HNSCC biology.