Proverbs reflect social and moral norms, ways of behavior, thoughts, traditions and customs, namely the culture of a nation. A significant part of the culture of a nation is reflected in human relations, that are based on the concept that we refer to as friendship. The concept of friendship can be considered the most significant and valuable concept of humanity. This concept is an ancestral heritage that is being carried into the future. This heritage could reach the present through the use of proverbs and it will be carried into the future generations by the use of proverbs as well. A proverb is one of the means to reflect a nation’s identity. It is impossible to mention a nation without proverbs on earth, because there is no nation without proverbs. It is even possible to say that the most important feature that differentiates a nation from another is proverbs. The reason is that, proverbs highlight the cultural similarities and differences among various nations. Of course, one can also refer to the proverbs that a nation got or adopted from another. It is our duty of loyalty to introduce proverbs about friendship that are used quite often both in Turkish and Moldovan languages to the world of science. The primary objective of this article is to convey the definitions of the proverbs in both cultures, to emphasize the concept of friendship, to evaluate the Turkish and Moldovan cultures of friendship, and to determine the similarities and differences in proverbs related to friendship.