Objectives: This study aimed to determine and classify the reasons for cone-beam computed tomography (CBCT) imaging requests in the Oral and Maxillofacial Radiology Department, Istanbul University Faculty of Dentistry, and to examine which reasons more commonly require CBCT imaging. Material and methods: From the local CBCT database, 956 pediatric patients gave their consent. Subsequently, age, gender, the reason for referral, a field of view (FOV), and referral departments were collected. Patients were grouped according to age distribution as 1-6 years, 7-12 years, and 13-17 years. Descriptive and comparative statistical analysis was performed. Results: When CBCT referral reasons were analyzed, some of the most common requests were bone pathology (26.25%), impacted teeth (19.87%), dental anomalies (14.12%), cleft lip, and palate (13.91%), respectively. When referral reasons are evaluated according to age groups, dentoalveolar trauma (p=0.049), impacted teeth (p=0.000), dental anomalies, surgical applications (p=0.021), bone pathology (p=0.004), cleft lip and palate statistically significant differences were found between the (p=0.000) indications and age groups (p=0.000). Conclusion: This study can guide dental practitioners in referring pediatric patients for three-dimensional imaging.