The utility of FDG-PET/CT as an effective tool for detecting recurrent colorectal cancer regardless of serum CEA levels

Sanli Y., Kuyumcu S., Ozkan Z. G., Kilic L., Balik E., Turkmen C., ...More

ANNALS OF NUCLEAR MEDICINE, vol.26, no.7, pp.551-558, 2012 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 7
  • Publication Date: 2012
  • Doi Number: 10.1007/s12149-012-0609-0
  • Journal Name: ANNALS OF NUCLEAR MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.551-558
  • Keywords: Colorectal cancer, Recurrence, CEA levels, FDG-PET/CT, POSITRON-EMISSION-TOMOGRAPHY, CARCINOEMBRYONIC ANTIGEN, COMPUTED-TOMOGRAPHY, F-18-FDG PET, RESECTION, IMPACT, METASTASES, SURVIVAL, CT
  • Istanbul University Affiliated: Yes

Abstract

Tumor recurrence of colorectal cancers (CRC) is generally followed up by analyses of the serum carcinoembryonic antigen (CEA) levels. However, recent evidence suggests that tumor recurrence can also be visualized by 18F-fluoro-deoxyglucose emission tomography/computed tomography (FDG-PET/CT) in patients with normal CEA levels. We retrospectively evaluated the diagnostic performance of FDG-PET/CT in patients with suspected recurrence of CRC by comparing PET/CT performance in patients with normal CEA levels with PET/CT performance in patients with elevated CEA levels.