Intraportal Transplantation of Pancreatic Islets in Mouse Model

Khatri R., Hussmann B., Rawat D., Gurol A. O., Linn T.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, sa.135, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: Sayı: 135
  • Basım Tarihi: 2018
  • Doi Numarası: 10.3791/57559
  • Dergi Adı: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • İstanbul Üniversitesi Adresli: Evet

Özet

Pancreatic islet transplantation to reduce hyperglycemia is highly successful in rodents with chemically-induced diabetes. The most common transplantation site in experimental islet transplantation is the kidney capsule. However, as less is known about the interaction of pancreatic islets with blood constituents, it also makes sense to utilize the portal vein approach in experimental islet transplantation.