Nutrition, cilt.147, 2026 (SCI-Expanded, Scopus)
Objectives Sarcopenia, traditionally considered an aging-related condition, is increasingly being recognized in pediatrics, where low muscle mass (LMM) affects growth and health outcomes. LMM is also a hallmark of malnutrition. Normative muscle mass (MM) values are critical for assessing LMM in children, yet current references are limited to a few studies conducted in specific populations, underscoring the need for further research. The aim of this study was to establish age- and sex-specific reference values for MM indicators in healthy children, representing a new population cohort. Methods A cross-sectional analysis of healthy children aged 5–14 y was conducted. The bioelectrical impedance analysis technique, using equipment that enables the evaluation of body composition in children (Tanita DC360, Tokyo, Japan), was used to evaluate body composition. The percentile values for fat-free mass (FFM) and MM were calculated by age and indexed according to weight, height squared, and body mass index. Results A total of 844 healthy children (388 girls and 456 boys) were included, with age- and sex-specific percentiles for FFM and MM established. Comparative analyses with previously studied populations were also performed. Reference values for FFM and MM adjusted by body mass index were reported for the first time. Conclusions This study provides normative reference values for MM indicators in children, offering a valuable tool for monitoring growth and diagnosing conditions such as sarcopenia and malnutrition. Further research in diverse populations is recommended to enhance the accuracy of LMM assessment.