An Investigation of <i>SDF1/CXCR4</i> Gene Polymorphisms in Autism Spectrum Disorder: A Family-Based Study.
Psychiatry investigation, vol.15, no.3, pp.300-305, 2018 (SCI-Expanded, SSCI, Scopus)
- Publication Type: Article / Article
- Volume: 15 Issue: 3
- Publication Date: 2018
- Doi Number: 10.30773/pi.2017.05.31.2
- Journal Name: Psychiatry investigation
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
- Page Numbers: pp.300-305
- Istanbul University Affiliated: Yes
Abstract
Objective Autism spectrum disorders (ASD) have a complex pathophysiology including genetic, inflammatory and neurodevelopmental components. We aim to investigate the relationship between ASD and gene polymorphisms of stromal cell-derived factor-1 (SDF-1) and its receptor CXC chemokine receptor-4 (CXCR4), which may affect inflammatory and neurodevelopmental processes.