Investigation of DNA repair genes in patients with obsessive-compulsive disorder

Celik R., Iplik E. S., Kucukali C. İ., Tuzun E., Cakmakoglu B.

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, vol.26, no.8, pp.1269-1273, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 8
  • Publication Date: 2017
  • Doi Number: 10.17219/acem/66698
  • Journal Name: ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1269-1273
  • Keywords: polymorphism, obsessive-compulsive disorder, DNA repair, XPD, BASE-EXCISION-REPAIR, ALZHEIMERS-DISEASE, LUNG-CANCER, POLYMORPHISMS, NEURONS, DAMAGE, XRCC1, RISK, APE1, GENETICS
  • Istanbul University Affiliated: Yes

Abstract

Background. Obsessive-compulsive disorder (OCD) is a major psychiatric disorder identified mostly by obsessions and compulsions. Molecular genetic and gene-expression studies focused on familial and twin cases have shown a wide variety of variant genes related to OCD.