Association of polymorphisms in the sex hormone genes with the presence and severity of coronary artery disease

Coban N., Ozuynuk A. S., Erkan A. F., KAYA A., EKİCİ B., Guclu-Geyik F., ...Daha Fazla

TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY, cilt.50, sa.1, ss.22-33, 2022 (ESCI) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 50 Sayı: 1
  • Basım Tarihi: 2022
  • Doi Numarası: 10.5543/tkda.2022.17203
  • Dergi Adı: TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.22-33
  • Anahtar Kelimeler: Coronary artery disease, genetics, estrogen receptor alpha, single nucleotide polymorphism, aromatase, ESTROGEN-RECEPTOR-ALPHA, SINGLE-NUCLEOTIDE POLYMORPHISM, BLOOD-PRESSURE, CYP19A1 GENE, POSTMENOPAUSAL WOMEN, INSULIN-RESISTANCE, RISK, HEART, CANCER, ATHEROSCLEROSIS
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objective: Coronary artery disease (CAD) is an important public health problem worldwide. Therefore, it is important to identify the molecular mechanisms and the candidate gene polymorphisms involved in the development of CAD. In this study, we focused on 2 polymorphisms of the atherosclerosis-related genes, ESR1 and CYP19A1.