Germline mutations of aryl hydrocarbon receptor-interacting protein (AIP) gene and somatostatin receptor 1-5 and AIP immunostaining in patients with sporadic acromegaly with poor versus good response to somatostatin analogues


Ozkaya H. M., Comunoglu N., Sayitoglu M., Keskin F. E., Firtina S., Khodzhaev K., ...Daha Fazla

PITUITARY, cilt.21, ss.335-346, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1007/s11102-018-0876-4
  • Dergi Adı: PITUITARY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.335-346
  • Anahtar Kelimeler: Somatostatin analogue, Receptor, Resistance, SECRETING PITUITARY-ADENOMAS, NEUROENDOCRINE TUMORS, SSTR2 EXPRESSION, OCTREOTIDE LAR, YOUNG-PATIENTS, SOMATOTROPINOMAS, PREVALENCE, RESISTANCE, COHORT, MACROADENOMAS
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objective To determine aryl hydrocarbon interacting protein (AIP) gene variations and AIP and somatostatin receptor (SSTR) 1-5 immunostaining in patients with apparently sporadic acromegaly with poor versus good response to somatostatin analogues (SRLs).