Generalized allergic contact dermatitis from polysensitization to strong (nitrofurazone) and weak (ichthammol, polyethylene glycol) contact sensitizers in a patient with stasis dermatitis

Özkaya E., Turgut H. D.

Contact Dermatitis, cilt.90, sa.2, ss.192-195, 2024 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 90 Sayı: 2
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1111/cod.14459
  • Dergi Adı: Contact Dermatitis
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, BIOSIS, CAB Abstracts, EMBASE, Veterinary Science Database
  • Sayfa Sayıları: ss.192-195
  • Anahtar Kelimeler: allergic contact dermatitis, case report, ichthammol, ichthyol, nitrofurazone, patch test, polyethylene glycol, polysensitization, stasis dermatitis
  • İstanbul Üniversitesi Adresli: Evet

Özet

The risk of contact sensitization is increased in chronic inflamed skin conditions such as stasis dermatitis. Nitrofurazone, also known as 'yellow ointment', is a strong contact sensitizer and still a significant culprit of allergic contact dermatitis (ACD) in Turkey.(1) Nitrofurazone allergy is frequently associated with concomitant contact sensitization to polyethylene glycol (PEG), a weak contact allergen and the vehicle component of nitrofurazone ointment.(1) Ichthammol, another wellknown traditional topical drug known as 'black ointment', is also a weak contact sensitizer.(2) There are only a few case reports of ichthammol-induced ACD in the literature,(2-4) the most recent one published in the early 1980s. Here, we present a rare patient with generalized ACD due to polysensitivity from nitrofurazone, PEG and ichthammol from concomitant use of these topical preparations to treat his stasis dermatitis.