Impact of Topiramate on Rat Phrenic Nerve-Hemidiaphragm Preparations


Kucukali C. I. , Tuzun E. , NURTEN A.

NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, vol.54, no.3, pp.202-204, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 54 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.5152/npa.2017.19422
  • Title of Journal : NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY
  • Page Numbers: pp.202-204

Abstract

Introduction: Topiramate has a negative modulatory effect on voltage-gated ion channels involved in neuromuscular junction transmission. To investigate the potential impact of topiramate on muscle contraction, phrenic nerve-hemidiaphragm preparations were used as a neuromuscular junction model.