Expression of antimicrobial peptides in recurrent adenotonsillitis

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Demir M. G., Aydin S., ERDOGAN B. A., Oguztuzun S., Kilic M., BARISIK N. O.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.41, no.6, pp.437-442, 2016 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 41 Issue: 6
• Publication Date: 2016
• Doi Number: 10.1515/tjb-2016-0145
• Journal Name: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
• Page Numbers: pp.437-442
• Istanbul University Affiliated: No

Abstract

Background: Recurrent acute tonsillitis is one of the most frequent otorhinolaryngology clinic referrals, yet its pathogenesis remains poorly understood. Antimicrobial cationic peptides are components of the innate system. They are generally small, highly positively charged peptides with broad spectrum antimicrobial activity which function as the body's "natural antibiotics". Our aim is to investigate the role of antimicrobial cationic peptides in the susceptibility of patients to recurrent acute tonsillitis.