Copy number profiling of tumor suppressor genes in head and neck cancer

Yalniz Z., Demokan S., Karabulut B., Ulusan M., Suoglu Y., Dalay N.

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, vol.39, no.2, pp.341-346, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 2
  • Publication Date: 2017
  • Doi Number: 10.1002/hed.24593
  • Journal Name: HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.341-346
  • Keywords: copy number change, tumor suppressor genes, head and neck cancer, multiplex ligation-dependent probe amplification (MLPA) analysis, tissue inhibitor of metalloproteinase 3 (TIMP3) amplification, SQUAMOUS-CELL CARCINOMA, PROMOTER HYPERMETHYLATION, CHROMOSOMAL-ABERRATIONS, MULTIPLE GENES, TIMP3, AMPLIFICATION, METHYLATION, EXPRESSION, CDKN2A, INSTABILITY
  • Istanbul University Affiliated: Yes

Abstract

Background. Sensitive and reliable new biomarkers are needed in head and neck cancer to predict the outcome and for therapy that is more effective. Copy number alterations are frequent and play a critical role in cancer.