Preserving Charge and Oxidation State of Au(III) Ions in an Agent-Functionalized Nanocrystal Model System

Muellegger S., Schoefberger W., Rashidi M., Lengauer T., Klappenberger F., Diller K., ...More

ACS NANO, vol.5, no.8, pp.6480-6486, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 5 Issue: 8
  • Publication Date: 2011
  • Doi Number: 10.1021/nn201708c
  • Journal Name: ACS NANO
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.6480-6486
  • Keywords: gold(III), porphyrin, frontier orbitals, functional, nanotemplate, oxidation state stabilization, STM, SURFACE, AU(111), AU, ANTICANCER, PORPHYRINS, COMPLEXES, APOPTOSIS
  • Istanbul University Affiliated: No


Supporting functional molecules on crystal facets is an established technique in nanotechnology. To preserve the original activity of ionic metallorganic agents on a supporting template, conservation of the charge and oxidation state of, the active center is indispensable. We. present a model system of a metallorganic agent that, indeed, fulfills this design criterion on a technologically relevant metal support With potential Impact on Au(III)-porphyrin-functionalized nanoparticles for an improved anticancer-drug delivery. Employing scanning tunneling microscopy and -spectroscopy in combination with photoemission spectroscopy,we clarify at the single-molecule level the underlying mechanisms of this exceptional adsorption mode. It is based on the balance between a high-energy oxidation state and an electrostatic screening-response of the surface (image charge). Modeling with first principles methods reveals submolecular details of the metal-ligand bonding interaction and completes the study by providing an Illustrative electrostatic.. model relevant for ionic metalorganic agent molecules, in general.