13th Biennial Congress of the European Association of Oral Medicine, Turin, İtalya, 15 - 17 Eylül 2016, cilt.22, sa.29, ss.48
Oral cancer in young people: 10
years retrospective
Objectives:Oral cancer is the sixth
most common of cancers worldwide. In last two dec-ades there were many reports
emerging about young people having oral cancer, which isknown as having a peak
during the sixth decades. In this study we aimed to evaluate theyoung people
having oral cancer about etiologic factors.
Methods:The data was retrospectively
collected from the archives at Istanbul University,Oncology Institute,
Radiation Oncology Department. 51 patients (19 female, 32 male)who were treated
for oral cancer between years 2005-2015 and aged between 18 and 45were
reviewed.Statistical data was evaluated with IBM 22.0 programme and statistical
significance wastaken as P<0.05.
Results:The most common location was
the tongue 27.5% followed by the hard palate15.7% and the base of tongue 13.7%.
In terms of etiologic factors smoking, alcohol, fam-ily history of cancer were
investigated. Smoking was found significantly higher in males(P=0.0001) but not
statistically significant between age groups. Alcohol consumptionwas also found
significantly higher in males (P=0.003) but not significant between agegroups.
Family history of cancer results were similar between groups. Nodal
metastasisresults between age groups found statistically significant.Higher
aged group had more nodal metastasis (P=0.05). Histologic grading was alsofound
statistically significant in comparison of age groups. The higher aged group
hadmore poor differentiation than younger aged group (P=0.032).
Conclusion:The risk factors we
evaluated in this study have similar results with higherage groups. In the
limitations of this study we could not compare HPV infection anddietary
factors. However further investigations in larger groups, possibly
prospectivelyconducted, could shed more light on risk factors of younger people
having oral cancer.
Relevance:Major avoidable
risk factors for oral cancer seems to be similar whicheverage group we concern.
More efforts both by clinicians and governments are needed, espe-cially to
prevent the use of tobacco products.