This study contains the results of ethnobotanical investigations carried out to determine what plants are used by the people of Elmasuyu village in the Sivrice district of Elazığ. For this purpose, several field studies were conducted in 2018 and 2019 in Elmasuyu village. During the field studies, 76 plant specimens were collected and identified and ethnobotanical information concerning these plants was recorded. The voucher specimens were stored in the Herbarium of the Faculty of Pharmacy, Istanbul University (ISTE) and in the personal herbarium of Rümeysa GÜL (RG). Ethnobotanical uses of the plants were recorded by interviewing volunteers from the people of Elmasuyu village. The study was focused on identifying the collected species, on the diseases treated by them, parts of the used plants, methods of preparation and administration. FIC values and Use Values were calculated to identify the potentially effective medicinal plants. Data obtained in Elmasuyu village were compared with those from the earlier ethnobotanical studies in Eastern Anatolia.