Glycoprotein Levels and Oxidative Stomach Damage in Diabetes and Prostate Cancer Model: Protective Effect of Metformin

Ertik O., Aydin P. K., BULAN N. Ö., YANARDAĞ R.

Acta Chimica Slovenica, ss.574-587, 2023 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2023
  • Doi Numarası: 10.17344/acsi.2023.8198
  • Dergi Adı: Acta Chimica Slovenica
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Central & Eastern European Academic Source (CEEAS), Chemical Abstracts Core, EMBASE, MEDLINE, Directory of Open Access Journals, DIALNET
  • Sayfa Sayıları: ss.574-587
  • Anahtar Kelimeler: Diabetes, Dunning Prostate Cancer, Metformin, Oxidative Stress, Stomach Damage
  • İstanbul Üniversitesi Adresli: Evet

Özet

People with diabetes have a higher risk of prostate cancer and people with prostate cancer are prone to stomach metastases. Therefore, researchers continue to search for new approaches in the treatment of individuals with all the above diseases at the same time. The protective effect of metformin (which is used in the treatment of diabetes) on cancer continues to be supported by studies. In this study, it was determined that the biochemical parameters showed a protective effect on stomach tissues with the administration of metformin to cancer and group with both cancer and diabetes groups. With the principal component analysis, it was determined that the biochemical parameters studied in the stomach tissue showed a correlation.