Evaluation of cognitive functions in individuals with synthetic cannabinoid use disorder and comparison to individuals with cannabis use disorder

Cengel H. Y., Bozkurt M., Evren C., Umut G., Keskinkilic C., Agachanli R.

PSYCHIATRY RESEARCH, cilt.262, ss.46-54, 2018 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 262
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.psychres.2018.01.046
  • Dergi Adı: PSYCHIATRY RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Sayfa Sayıları: ss.46-54
  • Anahtar Kelimeler: Synthetic cannabinoid, Cannabis, Cognitive functions, Spice, EPISODIC MEMORY, CB1 RECEPTORS, HUMANS, ATTENTION, PERFORMANCE, CEREBELLUM, BRAIN, INHIBITION, DEPENDENCE, MARIJUANA
  • İstanbul Üniversitesi Adresli: Evet

Özet

The use of synthetic cannabinoid has been increasing throughout the world and has become a major public health problem. The present study aims to investigate the attention, memory, visuospatial and executive functions in individuals with synthetic cannabinoid use disorder and compare the results with findings obtained from individuals with cannabis use disorder and healthy volunteers with no substance use. Fifty-two patients with synthetic cannabinoid use disorder, 45 patients with cannabis use disorder and 48 healthy control group males were included in the study. The neuropsychological test battery was designed to involve ten studies evaluating a large series of cognitive functions. Impairments in attention, memory, executive and visuospatial functions were identified in individuals with synthetic cannabinoid use disorder and these impairments were found to be significantly greater than in individuals with cannabis use disorder and healthy controls. In line with the data obtained from this study; the evaluation of each cognitive function with more comprehensive test batteries and supporting these evaluations with sensitive brain imaging studies are important topics for future research.