Effect of maternal and infant vitamin D supplementation on vitamin D levels of breastfed infants

Bugrul F., Devecioglu E., Ozden T., Gokcay G., Omer B.

TURKISH JOURNAL OF PEDIATRICS, cilt.55, sa.2, ss.158-163, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 55 Sayı: 2
  • Basım Tarihi: 2013
  • Dergi Adı: TURKISH JOURNAL OF PEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.158-163
  • Anahtar Kelimeler: breastfed infants, lactating women, maternal vitamin D supplementation, vitamin D deficiency, D DEFICIENCY, PREGNANT-WOMEN, NEWBORNS, INSUFFICIENCY, MOTHERS
  • İstanbul Üniversitesi Adresli: Evet

Özet

The aim of our study was to investigate the effect of maternal vitamin D-3 (400 U/day) supplementation on breastfed infants at 6 months of age. Mothers (n=96) were enrolled within 1 month after birth and assigned to the 400 IU/day regimen or no vitamin D-3 supplementation for 6 months. All infants received 400 IU/day of vitamin D-3 and were exclusively breastfed until 4 months of age. Of all mothers, 22.2% had vitamin D levels above 20 ng/ml initially. At the end of the study, vitamin D levels of mothers and their infants were similar in both groups. Thirteen percent of the infants in the intervention group and 20.5% in the control group had vitamin D levels below 12 ng/ml. Serum 25-hydroxyvitamin D (25(OH) D) concentrations at 6 months had increased significantly in mothers in the intervention group. Lactating mothers and their children need vitamin D supplementation but further studies are required with higher doses.