Case report of fatal Mycobacterium tilburgii infection

Akpinar T. S., Bakkaloglu O. K., Ince B., Tufan F., Kose M., Poda M., ...More

JOURNAL OF INFECTION AND CHEMOTHERAPY, vol.21, no.7, pp.538-540, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 7
  • Publication Date: 2015
  • Doi Number: 10.1016/j.jiac.2015.02.006
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.538-540
  • Keywords: Atypical mycobacteria, Mycobacterium tilburgii, 16S rRNA gene sequencing, IDENTIFICATION, DIAGNOSIS, PATIENT, DISEASE
  • Istanbul University Affiliated: Yes


There are few reports concerning Mycobacterium tilburgii infection in humans because this bacterium is non-cultivatable. Herein, using new molecular techniques, we report the case of an immunocompromised patient with fatal disseminated lymphadenitis that was caused by M. tilburgii. 26 years old Caucasian HIV negative female patient presented with abdominal pain. Her clinical assessment revealed disseminated lymphadenitis, that was acid fast bacilli positive. Further molecular evaluation showed the causative agent as M. tilburgii. Despite anti mycobacterial therapy and careful management of intervening complications patient died because of an intraabdominal sepsis.