An anthropomorphic body phantom for the determination of calibration factor in radionuclide treatment dosimetry.


Kovan B., Demir B., Işık E. G., Has Şimşek D., Özkan Z. G., Kuyumcu S., ...More

Radiation protection dosimetry, 2023 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume:
  • Publication Date: 2023
  • Doi Number: 10.1093/rpd/ncad176
  • Journal Name: Radiation protection dosimetry
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Applied Science & Technology Source, Biotechnology Research Abstracts, CAB Abstracts, Chimica, EMBASE, Environment Index, Index Islamicus, INSPEC, MEDLINE, Pollution Abstracts, Veterinary Science Database
  • Istanbul University Affiliated: Yes

Abstract

The aim of this study is to create an inhomogeneous human-like phantom, whose attenuation and scattering effects are similar to the human body, as an alternative to the homogeneous phantoms traditionally used in calibration factor (CF) determination. The phantom was designed to include the thorax, abdomen and upper pelvis regions sized to represent a 75-kg male with a body mass index of 25. Measurements using Lu-177 with 50- and 100-mL lesion volumes were performed using inhomogeneous anthropomorphic body phantom (ABP) and homogeneous NEMA PET body phantom. There was a difference of 5.7% of Calibration Factor including attenuation and scatter effect between ABP and NEMA PET body phantom. Because it better reflects the attenuation and scatter effect, it is recommended to use a human-like inhomogeneous phantom for determination of CF instead of a homogeneous phantom.