An association analysis at 2q36 reveals a new candidate susceptibility gene for juvenile absence epilepsy and/or absence seizures associated with generalized tonic-clonic seizures

Yalcin O., Baykan B., Agan K., Yapici Z., Yalcin D., Dizdarer G., ...More

EPILEPSIA, vol.52, no.5, pp.975-983, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 52 Issue: 5
  • Publication Date: 2011
  • Doi Number: 10.1111/j.1528-1167.2010.02970.x
  • Journal Name: EPILEPSIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.975-983
  • Istanbul University Affiliated: Yes


Purpose: To further evaluate the previously shown linkage of absence epilepsy (AE) to 2q36, both in human and WAG/Rij absence rat models, a 160-kb region at 2q36 containing eight genes with expressions in the brain was targeted in a case-control association study involving 205 Turkish patients with AE and 219 controls.