Disappearing Inferior Vena Cava in A Pediatric Patient with Down Syndrome and Hereditary Thrombophilia


Petik B., ÇEVİK M. Ö., Sirik M., Colak D., ERTÜRK Ş. M.

JOURNAL OF THE BELGIAN SOCIETY OF RADIOLOGY, cilt.100, sa.1, 2016 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Editöre Mektup
  • Cilt numarası: 100 Sayı: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5334/jbr-btr.975
  • Dergi Adı: JOURNAL OF THE BELGIAN SOCIETY OF RADIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Anahtar Kelimeler: Disappearing Inferior Vena Cava, Hereditary Thrombophilia, IVC, Down syndrome, homozygous MTHFR polymorphism, CEREBRAL VENOUS THROMBOSIS, FACTOR-V-LEIDEN, CONGENITAL ABSENCE, RISK FACTOR
  • İstanbul Üniversitesi Adresli: Evet

Özet

Absence of the infrarenal segment of the inferior vena cava is an extremely rare anomaly. The reasons for such a developmental failure are unclear. Most researchers believe that the cause lies in embryonic dysgenesis affecting separate segments or the entire inferior vena cava. Others suggest that absence of the inferior vena cava is not embryonic in origin, rather the result of intrauterine or perinatal thrombosis. We report a case here that during a period of six months, inferior vena cava first occluded, then become redundant in a baby girl with several chromosomal and gene defects, including Down syndrome and hereditary thrombophilia, admitted to our hospital due to the swelling and redness of the right lower extremity. From this observation, we propose that the absence of the inferior vena cave was not of embryonic origin but due to thrombosis.