The induction of oxidative stress, cytotoxicity, and genotoxicity by dental adhesives

Demirci M., Hiller K. -., Bosl C., Galler K., Schmalz G., Schweikl H.

DENTAL MATERIALS, cilt.24, sa.3, ss.362-371, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Sayı: 3
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.dental.2007.06.009
  • Dergi Adı: DENTAL MATERIALS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.362-371
  • Anahtar Kelimeler: dental adhesives, cytotoxicity, genotoxicity, reactive oxygen species, IN-VITRO CYTOTOXICITY, CELL-CYCLE ARREST, HUMAN PULP CELLS, BONDING AGENTS, GINGIVAL FIBROBLASTS, RESIN MONOMERS, ROS PRODUCTION, T-ANTIGEN, APOPTOSIS, ACRYLAMIDE
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objectives. Polymerized dental resin materials release residual monomers that may interact with pulp tissues. We hypothesized that dental adhesives might cause cytotoxicity in pulp cells via the generation of reactive oxygen species (ROS), which may also contribute to genotoxic effects in vitro.