Design of One-Dimension Photonic Crystal-Based Biosensor Working in Visible Regıon for Non-Invasiv Detectıon of Varıous Cancer and Blood Cells

Çetinkaya Ç.

TURKISH PHYSICAL SOCIETY 38th INTERNATIONAL PHYSICS CONGRESS, Muğla, Turkey, 31 August - 04 September 2022, pp.201

  • Publication Type: Conference Paper / Summary Text
  • City: Muğla
  • Country: Turkey
  • Page Numbers: pp.201
  • Istanbul University Affiliated: Yes


In this study, we present a biosensor design with a resonance cavity formed by MgF2/MoO3-based one-dimensional photonic crystals designed in the visible region, which can be used to Non-Invasive detect different blood components and various cancerous cells. We examined the sensor properties of the designed biosensors that the human eye can detect by adjusting the resonance wavelengths at 500 nm. We examined various design parameters so the resonance cavity biosensor can detect various blood components such as blood plasma, hemoglobin, glucose, biotin Streptavidin, and Bovine Serum Albumin. In addition, we determined the shifts in the resonance wavelength so that the biosensor can be used to detect cancer cells such as Jurkat, Hela, PC12, MDA-MB- 231, and MCF-7. We calculated the designed biosensors' optical characteristics and sensor performance parameters with the Transfer Matrix Method. The sensor performance parameters of the designed biosensor and the amount of shift from the resonance wavelength were evaluated together. The greatest deviation from the resonance wavelength for blood components was observed in Bovine Serum Albumin. This shift in the detection of cancer cells was greatest in MCF-7.