Brain Infiltration of Immune Cells in CASPR2-Antibody Associated Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis

Unverengil G., Vanli Yavuz E. N., Tuzun E., Erdag E., Kabadayi S., Bilgic B., ...Daha Fazla

NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, cilt.53, sa.4, ss.344-347, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 53 Sayı: 4
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5152/npa.2016.15932
  • Dergi Adı: NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.344-347
  • Anahtar Kelimeler: Antibody, CASPR2, hippocampal sclerosis, temporal lobe epilepsy, autoimmunity, ANTI-NMDAR ENCEPHALITIS, LIMBIC ENCEPHALITIS, FOCAL EPILEPSY, ANTIBODIES, AUTOANTIBODIES, COMPLEMENT
  • İstanbul Üniversitesi Adresli: Evet

Özet

Introduction: Antibodies directed against neuronal surface antigens have recently been identified in patients with focal temporal lobe epilepsy (TLE) of unknown cause and mesial TLE with hippocampal sclerosis (MTLE-HS), thereby emphasizing the role of autoimmunity in TLE. Antibodies to contactin-associated protein-like 2 (CASPR2) are prevalent in MTLE-HS patients. We aimed to find out whether anti-neuronal autoimmunity might be involved in CASPR2 antibodyrelated MTLE-HS.