Prof. Yasemin AYDIN

Publication Network

Articles 33

1. The insecticide chlorpyrifos leads to genotoxic effects by triggering oxidative stress and apoptosis in Sertoli cells

AYDIN Y., Kurtel H., Cakir E., ORTA YILMAZ B.

Toxicology and Industrial Health , vol.41, no.12, pp.550-562, 2025 (SCI-Expanded, Scopus)

2. 5-Hydroxymethylfurfural causes reproductive toxicity in male mice by increasing oxidative stress and apoptosis through the Nrf2/HO-1 signaling pathway.

Aydin Y., Sarialioglu I., Armut G., Calmaz E., Orta Yilmaz B.

Toxicology mechanisms and methods , pp.1-17, 2025 (SCI-Expanded)

3. Luteolin Protects Against Acrylamide-Induced Cellular Toxicity in Mouse Leydig Cells

Calmaz E., ORTA YILMAZ B., AYDIN Y.

Food Science and Nutrition , vol.13, no.7, 2025 (SCI-Expanded)

4. Modulation of the Nrf2/HO-1 Pathway- and Apoptosis-Related Genes Following 5-hydroxymethylfurfural Induced Mouse Liver Injury

Kurtel H., AYDIN Y., ORTA YILMAZ B.

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY , vol.39, no.7, 2025 (SCI-Expanded)

5. The role of luteolin in modulation of acrylamide-induced genotoxicity and apoptosis in embryonic fibroblast cells

Keskin B., Orta Yılmaz B., Aydin Y.

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS , vol.902, 2025 (SCI-Expanded) Sustainable Development

6. Furan impairs cell function by inducing oxidative stress, DNA damage and apoptosis in mouse Sertoli cells in vitro

AYDIN Y., Dikbasan Y. U., ORTA YILMAZ B.

Drug and Chemical Toxicology , vol.48, no.5, pp.1067-1079, 2025 (SCI-Expanded)

7. The impact of furan exposure on steroidogenesis in Leydig cells: cellular and molecular observations

Orta Yılmaz B., Korkut A., Aydın Y.

MOLECULAR BIOLOGY REPORTS , vol.51, pp.1047-1059, 2024 (SCI-Expanded)

8. New insights into the mechanisms underlying 5-hydroxymethylfurfural-induced suppression of testosterone biosynthesis in vivo and in vitro

Orta Yılmaz B., Aydin Y.

TOXICOLOGY AND APPLIED PHARMACOLOGY , vol.493, pp.1-10, 2024 (SCI-Expanded)

9. N-acetylcysteine attenuates sodium arsenite-induced oxidative stress and apoptosis in embryonic fibroblast cells

Taşçi T., Orta Yılmaz B., Aydın Y., Çalışkan M.

TOXICOLOGY RESEARCH , vol.13, no.4, 2024 (SCI-Expanded) Sustainable Development

10. Vitamin E and genistein generate a cytoprotective effect on polychlorinated biphenyl- induced oxidative stress in testicular Leydig cells

Aydın Y., Orta Yılmaz B., Erkan M.

TRAKYA UNIVERSITY JOURNAL OF NATURAL SCIENCES , vol.25, no.1, pp.1-10, 2024 (ESCI)

11. Assessment of the oxidative damage and apoptotic pathway related to furan cytotoxicity in cultured mouse Leydig cells

Aydin Y., Yilmaz B., Dikbasan Y. U., Orta-Yilmaz B.

TOXICOLOGY RESEARCH , vol.12, no.3, pp.400-407, 2023 (SCI-Expanded) Sustainable Development

12. Dynamic assessment of the relationship between oxidative stress and apoptotic pathway in embryonic fibroblast cells exposed to glycidamide: possible protective role of hesperidin

ORTA YILMAZ B., AYDIN Y.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH , vol.30, no.18, pp.53295-53308, 2023 (SCI-Expanded)

13. Furan promotes cytotoxic effects through DNA damage and cell apoptosis in Leydig cells

YILMAZ B. E., AYDIN Y., ORTA YILMAZ B.

Toxicology Mechanisms and Methods , vol.33, no.9, pp.796-805, 2023 (SCI-Expanded) Sustainable Development

14. Disruption of Leydig cell steroidogenic function by sodium arsenite and/or sodium fluoride

Orta Yilmaz B., Aydin Y.

THERIOGENOLOGY , vol.193, no.193, pp.146-156, 2022 (SCI-Expanded)

15. Synergistic effects of arsenic and fluoride on oxidative stress and apoptotic pathway in Leydig and Sertoli cells

Aydin Y., Orta Yılmaz B.

TOXICOLOGY , vol.475, pp.1-11, 2022 (SCI-Expanded) Sustainable Development

16. Effects of Curcumin on Sodium Arsenite Induced Neoplastic Cell Transformation in Balb/c 3T3 Cells

Demircioglu B., Aydin Y., Orta-Yilmaz B., Yildizbayrak N., Erkan M.

BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY , vol.64, pp.1-10, 2021 (SCI-Expanded) Sustainable Development

17. Vitamin C inhibits glycidamide-induced genotoxicity and apoptosis in Sertoli cells

ORTA YILMAZ B., Yildizbayrak N., AYDIN Y.

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY , vol.34, no.9, 2020 (SCI-Expanded)

18. Acrolein exerts a genotoxic effect in the Leydig cells by stimulating DNA damage-induced apoptosis

Yildizbayrak N., Orta-Yilmaz B., Aydın Y., Erkan M.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH , vol.27, no.13, pp.15869-15877, 2020 (SCI-Expanded) Sustainable Development

19. Comparison of endometrial prostanoid profiles in three infertile subgroups: the missing part of receptivity?

Demiral Keleş I., Ülgen E., Erkan M. B., Çelik S. E., Aydın Y., Önem A. N., et al.

FERTILITY AND STERILITY , vol.113, pp.670-679, 2020 (SCI-Expanded)

20. Protective effects of curcumin on biochemical and molecular changes in sodium arsenite-induced oxidative damage in embryonic fibroblast cells

Perker M. C., Yilmaz B. O., Yildizbayrak N., Aydin Y., Erkan M. B.

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY , vol.33, no.7, 2019 (SCI-Expanded)

21. Evaluation of citrinin-induced toxic effects on mouse Sertoli cells.

Aydin Y., Orta Yılmaz B., Yildizbayrak N., Korkut A., Kursun M. A., Irez T., et al.

Drug and chemical toxicology , pp.1-7, 2019 (SCI-Expanded)

22. Acrylamide and its metabolite glycidamide can affect antioxidant defenses and steroidogenesis in Leydig and Sertoli cells

Aydin Y.

TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY , vol.100, no.2, pp.247-257, 2018 (SCI-Expanded)

23. Evidence of acrylamide- and glycidamide-induced oxidative stress and apoptosis in Leydig and Sertoli cells

Yilmaz B., Yildizbayrak N., Aydın Y., Erkan M. B.

Human and Experimental Toxicology , vol.36, pp.1225-1235, 2017 (SCI-Expanded) Sustainable Development

24. Exposure to Sodium Fluoride via Drinking Water Cause Cytotoxicity and Oxidative Damage in Leydig Cells

Aydın Y.

TRAKYA UNIVERSITY JOURNAL OF NATURAL SCIENCES , vol.18, pp.115-122, 2017 (Peer-Reviewed Journal)

25. The toxic effects of polychlorinated biphenyl (Aroclor 1242) on Tm3 Leydig cells

Aydin Y., Erkan M.

TOXICOLOGY AND INDUSTRIAL HEALTH , vol.33, pp.636-645, 2017 (SCI-Expanded)

26. Macroscopic and Microscopic Examination of Seasonal Gonad Change in Alburnus istanbulensis (Battalgil, 1941) (Teleostei: Cyprinidae)

Hamzaoglu E., Ozulug M., Tunali Y., Erkan M.

TURKISH JOURNAL OF FISHERIES AND AQUATIC SCIENCES , vol.15, no.3, 2015 (SCI-Expanded)

27. Testicular development of male mice offsprings exposed to acrylamide and alcohol during the gestation and lactation period

Sen E., Tunali Y., Erkan M.

HUMAN & EXPERIMENTAL TOXICOLOGY , vol.34, pp.401-414, 2015 (SCI-Expanded)

28. Morphological and histochemical examination of male and female gonads in Homarus gammarus (L. 1758)

Erkan M. B., Ayun Y.

CENTRAL EUROPEAN JOURNAL OF BIOLOGY , vol.9, no.1, pp.37-48, 2014 (SCI-Expanded)

29. Histology of the androgenic gland in Eriphia verrucosa (Forskal, 1775) (Decapoda, Brachyura)

Erkan M. B., Tunali Y., Ekinci S., Kara S.

TURKISH JOURNAL OF ZOOLOGY , vol.34, no.1, pp.79-84, 2010 (SCI-Expanded)

30. MORPHOLOGY OF TESTIS AND VAS DEFERENS IN THE XANTHOID CRAB, ERIPHIA VERRUCOSA (FORSKAL, 1775) (DECAPODA: BRACHYURA)

Erkan M. B., Tunali Y., Balkis H., Oliveria E.

JOURNAL OF CRUSTACEAN BIOLOGY , vol.29, no.4, pp.458-465, 2009 (SCI-Expanded)

31. MALE REPRODUCTIVE SYSTEM MORPHOLOGY AND SPERMATOPHORE FORMATION IN ASTACUS LEPTODACTYLUS (ESCHSCHOLTZ, 1823) (DECAPODA: ASTACIDAE)

Erkan M. B., Tunali Y., Sancar-Bas S.

JOURNAL OF CRUSTACEAN BIOLOGY , vol.29, no.1, pp.42-50, 2009 (SCI-Expanded)

32. Seasonal variations in the ovary and testis of Eriphia verrucosa (Forskal, 1775) (Crustacea : Decapoda) from Karaburun, SW Black Sea (SC)

Erkan M. B., Balkis H., Kurun A., Tunali Y.

PAKISTAN JOURNAL OF ZOOLOGY , vol.40, pp.217-221, 2008 (SCI-Expanded)

33. A structural study of functional cells in hepatopancreas of Mytilus galloprovincialis Lamarck, 1819

Tunali Y., Erkan M. B.

PAKISTAN JOURNAL OF ZOOLOGY , vol.40, no.2, pp.109-114, 2008 (SCI-Expanded)

Papers Presented at Peer-Reviewed Scientific Conferences 25

1. PROTECTIVE EFFECTS OF N-ACETYLSYSTEINE ON SODIUM FLUORIDEINDUCED CYTOTOXICITY AND APOPTOSIS IN MOUSE LEYDIG CELLS

Yılmaz Y., Kümbül Ö., Orta Yılmaz B., Aydın Y.

VI. International Agricultural, Biological & Life Science Conference, Edirne, Turkey, 18 - 20 September 2024, pp.345-355, (Full Text)

2. N-ACETYLCYSTEINE SUPPRESSES SODIUM FLUORIDE-INDUCED GENOTOXICITY IN MOUSE LEYDIG CELLS

Agalar A., Aydın Y., Orta Yılmaz B.

VI. International Agricultural, Biological & Life Science Conference, Edirne, Turkey, 18 - 20 September 2024, pp.680-690, (Full Text)

3. In vitro effects of luteolin on the toxicity of acrylamide in Leydig cells

Çalmaz E., Orta Yılmaz B., Aydın Y.

VI. International Conferences on Natural Sciences and Technologies, Antalya, Turkey, 30 May - 01 June 2024, pp.26, (Summary Text)

4. THE EFFECTS OF LUTEOLIN ON ACRYLAMIDE INDUCED OXIDATIVE DAMAGE IN 3T3 EMBRYONIC FIBROBLAST CELLS

Çakır E., Orta Yılmaz B., Aydın Y.

V. International Agricultural, Biological & Life Science Conference, Edirne, Turkey, 18 - 20 September 2023, pp.197-205, (Full Text)

5. IMPACT OF HESPERIDIN AGAINST GENOTOXIC RISKS CAUSED BY SODIUM FLUORIDE IN MICE LEYDIG

Armut G., Fakıoğlu İ., Aydın Y., Orta Yılmaz B.

V. International Agricultural, Biological & Life Science Conference, Edirne, Turkey, 18 - 20 September 2023, pp.103-111, (Full Text)

6. Luteolin alleviates genotoxicity by attenuating micronucleus formation and cellular damage in acrylamide-exposed embryonic fibroblast cells

Keskin B., Orta Yılmaz B., Aydın Y.

6th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2023) October 11-13, 2023. , Ankara, Turkey, 11 - 13 October 2023, pp.292, (Summary Text)

7. Effect of N-acetylcysteine on oxidative damage caused by arsenic in Leydig cells

Acı Kuşan C., Orta Yılmaz B., Aydın Y.

4th International Eurasian Conference on Science, Engineering and Technology (EurasianSciEnTech 2022), Ankara, Turkey, 14 - 16 December 2022, pp.374-381, (Full Text)

8. Examining the impact of furan on Sertoli cell function

Dikbasan Y. Ü., Aydın Y.

4th International Eurasian Conference on Science, Engineering and Technology (EurasianSciEnTech 2022), Ankara, Turkey, 14 - 16 December 2022, pp.47, (Summary Text)

9. ZINC AND VITAMIN C CAN PREVENT OXIDATIVE STRESS INDUCED BY LEAD NITRATE IN MOUSE LEYDIG CELLS

Sarıalioğlu İ., Keserci Y., Aydın Y., Orta Yılmaz B.

IV. International Agricultural, Biological & Life Science Conference, Edirne, Turkey, 29 - 31 August 2022, pp.191-201, (Full Text)

10. EFFECTS OF VITAMIN C AND ZINC ON FURAN INDUCED TOXICITY IN TM4 SERTOLI CELLS

Dumanoğlu Z., Orta Yılmaz B., Aydın Y.

IV. International Agricultural, Biological & Life Science Conference, Edirne, Turkey, 29 - 31 August 2022, pp.253-263, (Full Text)

11. Chlorpyripos induces cytotoxicity and genotoxicity in Sertoli cells

Aydın Y., Çakır E.

III. International Agricultural, Biological & Life Science Conference, Edirne, Turkey, 1 - 03 September 2021, pp.201, (Summary Text)

12. Antioxidant activity of ascorbic acid on sodium fluoride induced cytotoxicity, oxidative damage, and apoptosis in Leydig cells

Orta Yılmaz B., Aydın Y.

3rd International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2020), Ankara, Turkey, 19 - 20 March 2020, pp.15-22, (Full Text) Sustainable Development

13. Furan induces cytotoxicity, oxidative stress and apoptosis in Leydig cells

Dikbasan Y. Ü., AYDIN Y.

International Biodiversity & Ecology Sciences Symposium, İstanbul, Turkey, 26 - 28 September 2019, pp.184, (Summary Text)

14. Lipidomic analysis reveals increased TXA2 presence in non-receptive endometrium of recurrent miscarriage and repeated implantation failure patients

Bastu E., Demiral I., Ulgen E., Erkan M. B., Celik S. E., Aydin Y., et al.

34th Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology (ESHRE), Barcelona, Spain, 1 - 04 June 2018, vol.33, pp.337-338, (Summary Text)

15. Ameliorative effects of vitamin C on cellular oxidative damage and apoptosis induced by glycidamide in Sertoli cells

AYDIN Y., ORTA YILMAZ B.

International Congress on Engineering and Life Sciences, Kastamonu, Turkey, 26 - 29 April 2018, vol.1, no.1, pp.1, (Full Text)

16. Anti-Oxidative Effects of Curcumin on Sodium Arsenite Induced Oxidative Damage in 3T3 Embryonic Fibroblast Cells

ORTA YILMAZ B., AYDIN Y., Yıldızbayrak N., PERKER M. C., ERKAN M. B.

INTERNATIONAL EURASIAN CONFERENCE ON BIOLOGICAL AND CHEMICAL SCIENCES, Ankara, Turkey, 26 - 27 April 2018, vol.1, no.1, pp.356, (Full Text)

17. Co-exposure to sodium arsenite and sodium fluoride induced cellular and oxidative damage in Sertoli cells

ORTA YILMAZ B., AYDIN Y.

3rd International Congress on Environmental Researches and Technology (ICERAT), Belgrad, Serbia And Montenegro, 8 - 12 November 2017, pp.1-2, (Summary Text)

18. Whole-Genome Characterization and Composition of European Anchovy (Engraulis Encrasicolus L., 1758)

ELDEM V., Yüksel B., ERKAN M. B., Zararsız G., DİKMEN F., Saraç A., et al.

FABA 2016: International Symposium on Fisheries and Aquatic Sciences, Antalya, Turkey, 3 - 05 November 2016, pp.111-112, (Full Text)

19. Hamsi balığı (Engraulis Encrasicolus)’nın yumurta gelişiminde rol oynayan genlerin karşılaştırmalı transkriptomik yaklaşım ile belirlenmesi

ELDEM V., AYDIN Y., Yüksel B., ERKAN M. B.

II. Ulusal Su Ürünleri Yetiştiriciliğinde Gamet Biyolojisi Çalıştayı, Muğla, Turkey, 19 - 21 April 2016, pp.1, (Full Text)

20. Attenuating effect of Vitamin E and genistein on polychlorinated biphenyl (araclor 1242) induced oxidatyive damage and changes in steroidogenic enzymes in Leydig cells

ERKAN M. B., AYDIN Y.

9th Congress of the Turkish Society of Toxicology with Participation of the Hellenic Society of the Toxicology, İzmir, Turkey, 21 - 24 October 2015, pp.23, (Summary Text)

21. Effect of fluoride on Leydig cell viability, cytotoxicity and oxidative damage in vitro

Tunali Y.

51st Congress of the European-Societies-of-Toxicology (EUROTOX), Porto, Portugal, 13 - 16 September 2015, vol.238, (Summary Text)

22. Acrylamide and Its Metabolite Glycidamide can Effect Antioxidant System and Steroidogenesis in Leydig Cell in vitro

TUNALI Y., ERKAN M. B.

9th World Congress on Alternatives and Animal Use in the Life Sciences, Prag, Czech Republic, 24 - 28 August 2014, pp.136, (Full Text)

23. Effects of Acrylamide and Glycidamide on Antioxidant Systems and Steroidogenic Enzymes on TM4 Sertoli Cell

TUNALI Y.

9th World Congress on Alternatives and Animal Use in the Life Sciences, Prag, Czech Republic, 24 - 28 August 2014, pp.136, (Full Text)

24. Morphological And Histochemical Examination Of Gonads In Homarus Gammarus (L. 1758) (Decapoda, Homaridae)

ERKAN M., TUNALI AYUN Y.

The Crustacean Society Summer Meeting and 10th Collaquium Crustacea Decapoda Mediterranea in June 2012, in Athens-GREECE, Greece, 1 - 04 June 2012, pp.185, (Summary Text)

25. The male reproductive system in Nephrops norvegicus (Decapoda, Nephropoidae)

TUNALI AYUN Y.

The Crustacean Society Summer Meeting and 10th Collaquium Crustacea Decapoda Mediterranea in June 2012, in Athens-GREECE, Greece, 1 - 04 June 2012, pp.188, (Full Text)

Books 16

1. The Genotoxic Effects of Heat-Induced Food Contaminants in the Male Reproductive System

Orta Yılmaz B., Kurtel H., Keskin B., Aydın Y.

in: Genotoxicity: Advances in Research and Applications, Alimba Chibuisi Gideon, Editor, NOVA Science Publishers Inc. , New York, pp.1-31, 2024

2. Enhancement of Insulin Sensitivity and Management of Lipid Disorders during Gestational Diabetes Mellitus: Role of Capsaicin

Orta Yılmaz B., Korkut A., Aydın Y.

in: Natural Products and their Bioactives in Antidiabetic Drug Discovery, Pandey Kanti Bhooshan,Suttajit Maitree,Atukeren Pinar, Editor, John Wiley & Sons, West Sussex, UK , New Jersey, pp.294-307, 2024

3. The Role of Telomerase Activators in Antiaging Strategies and their Clinical Potential

Aydın Y., Orta Yılmaz B.

in: Emerging Anti-Aging Strategies, Rizvi,Syed Ibrahim, Editor, Springer Nature, Singapore, pp.227-242, 2023

4. Chapter 12 - Plant polyphenols in the regulation of ion channels during aging and induced diseases

ORTA YILMAZ B., YILMAZ B., AYDIN Y.

in: Plant Bioactives as Natural Panacea Against Age-Induced Diseases, Pandey Kanti Bhooshan, Suttajit Maitree, Editor, Elsevier, Amsterdam, pp.235-252, 2022

5. Chapter 5 - Plant bioactives in immune modulation and their role in antiaging

AYDIN Y., DİKBASAN Y. Ü., ORTA YILMAZ B.

in: Plant Bioactives as Natural Panacea Against Age-induced Diseases, Pandey Kanti Bhooshan, Suttajit Maitree, Editor, Elsevier, Amsterdam, pp.85-109, 2022

6. 16. Arsenic-induced oxidative stress in reproductive systems

Erkan M., Aydın Y., Orta Yılmaz B., Yıldızbayrak N.

in: Toxicology- Oxidative Stress and Dietary Antioxidants, Victor Preedy,Vinood Patel, Editor, AP, London , London, pp.145-153, 2021

7. 42. Protective effects of vitamin C against fluoride toxicity

Erkan M., Aydın Y., Orta Yılmaz B., Yıldızbayrak N.

in: Toxicology- Oxidative Stress and Dietary Antioxidants, Vinood Patel,Victor Preedy, Editor, AP, London , London, pp.435-442, 2021

8. Antiaging Strategies Based on Telomerase Activity

AYDIN Y.

in: Molecular Basis and Emerging Strategies for Anti-aging Interventions, Rizvi S.I., Çakatay U. , Editor, Springer, London/Berlin , Singapour, pp.97-109, 2018

9. Erkek Üreme Sistemi

TUNALI Y.

in: BRS Embriyoloji, İREZ T., ERKAN M., Editor, İstanbul Tıp Kitabevi, İstanbul, pp.180-191, 2016

10. Plazma Membranı

TUNALI Y.

in: Hücre Biyolojisi ve Histoloji, Hürdağ C., Editor, İstanbul Tıp Kitabevi, İstanbul, pp.1-14, 2016

11. The effects of Vitamin E on Genistein-Induced Oxidative Damage on TM3 Leydig cells

Kara-Ertekin S., Tunalı Y., Erkan M. B.

in: Perspectives in Animal Ecology and Reproduction, Gupta V.K.,Verma A.K.,Singh G.D., Editor, Daya Publishing House, New Delhi, pp.301-314, 2015

12. Protective role of Vitamin E on Polychlorinated Biphenyl (Aroclor 1260) induced oxidative damage and changes in steroidogenic enzymes in TM3 Leydig cell line

Tunalı Ayun Y., Erkan M.

in: Perpectives In Animal Ecology And Reproduction Vol.9, Gupta V. K.,Verma A. K.,Singh G. D., Editor, Daya Publishing House, New Delhi, pp.490-509, 2013

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