Association of Anti-Emetic Efficacy of Ondansetron with G2677T Polymorphism in a Drug Transporter Gene ABCB1 in Pakistani Population


Farhat K., Iqbal J., Waheed A., Mansoor Q., Ismail M., Pasha A. K.

JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN, cilt.25, sa.7, ss.486-490, 2015 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 7
  • Basım Tarihi: 2015
  • Dergi Adı: JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.486-490
  • Anahtar Kelimeler: ABCBl, Polymorphism, G2677T, Ondansetron, Postoperative nausea and vomiting, MULTIDRUG-RESISTANCE GENE, P-GLYCOPROTEIN, MDR1 GENE, POSTOPERATIVE NAUSEA, FREQUENCY, C3435T, EXPRESSION, ALLELE
  • İstanbul Üniversitesi Adresli: Hayır

Özet

Objective: To determine the association of ABCB1polymorphism G2677T with anti-emetic efficacy in patients treated with ondansetron for preventing postoperative nausea and vomiting.