Association of Anti-Emetic Efficacy of Ondansetron with G2677T Polymorphism in a Drug Transporter Gene ABCB1 in Pakistani Population

Farhat, Kulsoom; Iqbal, Javeid; Waheed, Akbar; Mansoor, Qaisar; Ismail, Muhammad; Pasha, Anwar

Association of Anti-Emetic Efficacy of Ondansetron with G2677T Polymorphism in a Drug Transporter Gene ABCB1 in Pakistani Population

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Farhat K., Iqbal J., Waheed A., Mansoor Q., Ismail M., Pasha A. K.

JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN, vol.25, no.7, pp.486-490, 2015 (SCI-Expanded)

Publication Type: Article / Article
Volume: 25 Issue: 7
Publication Date: 2015
Journal Name: JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.486-490
Keywords: ABCBl, Polymorphism, G2677T, Ondansetron, Postoperative nausea and vomiting, MULTIDRUG-RESISTANCE GENE, P-GLYCOPROTEIN, MDR1 GENE, POSTOPERATIVE NAUSEA, FREQUENCY, C3435T, EXPRESSION, ALLELE
Istanbul University Affiliated: No

Abstract

Objective: To determine the association of ABCB1polymorphism G2677T with anti-emetic efficacy in patients treated with ondansetron for preventing postoperative nausea and vomiting.