MEDIATORS OF INFLAMMATION, cilt.13, sa.1, ss.25-28, 2004 (SCI-Expanded)
Introduction: Helicobacter pylori ( H. pylori) is a non-invasive microorganism causing intense gastric mucosal inflammatory and immune reaction. H. pylori-induced gastric mucosal cytokine overproduction has been clearly documented previously. The stomach has a large surface area and continuous spill-over of locally produced cytokines into the blood stream is a possibility. There are few and conflicting data on circulatory proinflammatory cytokine levels in patients with H. pylori infection.