Serum levels of tumor necrosis factor-alpha, interleukin-6 and interleukin-8 are not increased in dyspeptic patients with Helicobacter pylori-associated gastritis

Bayraktaroglu T., Aras A., Aydemir S., Davutoglu C., Ustundag Y., Atmaca H., ...Daha Fazla

MEDIATORS OF INFLAMMATION, cilt.13, sa.1, ss.25-28, 2004 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 13 Konu: 1
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1080/09629350410001664789
  • Sayfa Sayıları: ss.25-28


Introduction: Helicobacter pylori ( H. pylori) is a non-invasive microorganism causing intense gastric mucosal inflammatory and immune reaction. H. pylori-induced gastric mucosal cytokine overproduction has been clearly documented previously. The stomach has a large surface area and continuous spill-over of locally produced cytokines into the blood stream is a possibility. There are few and conflicting data on circulatory proinflammatory cytokine levels in patients with H. pylori infection.