Serum levels of tumor necrosis factor-alpha, interleukin-6 and interleukin-8 are not increased in dyspeptic patients with Helicobacter pylori-associated gastritis
MEDIATORS OF INFLAMMATION, vol.13, no.1, pp.25-28, 2004 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 13 Issue: 1
- Publication Date: 2004
- Doi Number: 10.1080/09629350410001664789
- Journal Name: MEDIATORS OF INFLAMMATION
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.25-28
- Istanbul University Affiliated: No
Abstract
Introduction: Helicobacter pylori ( H. pylori) is a non-invasive microorganism causing intense gastric mucosal inflammatory and immune reaction. H. pylori-induced gastric mucosal cytokine overproduction has been clearly documented previously. The stomach has a large surface area and continuous spill-over of locally produced cytokines into the blood stream is a possibility. There are few and conflicting data on circulatory proinflammatory cytokine levels in patients with H. pylori infection.