Effect of a new synbiotic supplement on symptoms, stool consistency, intestinal transit time and gut microbiota in patients with severe functional constipation: a pilot randomized double-blind, controlled trial

Bazzocchi, G.; Giovannini, T.; Giussani, C.; Brigidi, P.; Turroni, S.

doi:10.1007/s10151-014-1201-5

Effect of a new synbiotic supplement on symptoms, stool consistency, intestinal transit time and gut microbiota in patients with severe functional constipation: a pilot randomized double-blind, controlled trial

Bazzocchi G., Giovannini T., Giussani C., Brigidi P., Turroni S.

TECHNIQUES IN COLOPROCTOLOGY, cilt.18, sa.10, ss.945-953, 2014 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 18 Sayı: 10
Basım Tarihi: 2014
Doi Numarası: 10.1007/s10151-014-1201-5
Dergi Adı: TECHNIQUES IN COLOPROCTOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.945-953
Anahtar Kelimeler: Functional constipation, Gut microbiota, Intestinal transit time, Stool consistency, Synbiotics, IRRITABLE-BOWEL-SYNDROME, QUALITY-OF-LIFE, FECAL MICROBIOTA, PROBIOTICS, DIAGNOSIS, LACTOBACILLUS, PRUCALOPRIDE, IMPACT, ADULTS
İstanbul Üniversitesi Adresli: Hayır

Özet

Background Data on the benefits of synbiotics in functional constipation are conflicting. The aim of this study was to assess whether the administration of the synbiotic supplement Psyllogel Megafermenti (R) normalized stool consistency and decreased intestinal transit time (ITT) in patients with severe functional constipation, based on its ability to impact on the gut microbiota.