NK cell subsets and their role in allergy

Deniz G., Akdiş M.

EXPERT OPINION ON BIOLOGICAL THERAPY, cilt.11, sa.7, ss.833-841, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 11 Sayı: 7
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1517/14712598.2011.572549
  • Dergi Adı: EXPERT OPINION ON BIOLOGICAL THERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.833-841
  • Anahtar Kelimeler: allergy, cytokines, cytotoxicity, NK cell subsets, NK cells, NATURAL-KILLER-CELLS, T-CELLS, ATOPIC-DERMATITIS, INHIBITORY RECEPTORS, MUCOSAL IMMUNITY, SURFACE-MOLECULE, DENDRITIC CELLS, INNATE IMMUNITY, TUMOR-CELLS, IN-VIVO
  • İstanbul Üniversitesi Adresli: Evet

Özet

Introduction: NK cells represent a distinct lymphocyte population with extensive cytolytic activity and a variety of other functions, including regulation of hemopoiesis, suppressor functions and immunoglobulin production. Recently, reports suggest that NK cells also display potent regulatory functions via secretion of cytokines or cell-contact-dependent mechanisms. Thus NK cells may regulate innate and adaptive immune responses and play a role in immune homeostasis.