Adrenomedullin in cirrhotic and non-cirrhotic portal hypertension

TAHAN V., AVŞAR E., KARACA C., Uslu E., EREN F., Aydin S., ...Daha Fazla

WORLD JOURNAL OF GASTROENTEROLOGY, cilt.9, sa.10, ss.2325-2327, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9 Sayı: 10
  • Basım Tarihi: 2003
  • Doi Numarası: 10.3748/wjg.v9.i10.2325
  • Dergi Adı: WORLD JOURNAL OF GASTROENTEROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2325-2327
  • İstanbul Üniversitesi Adresli: Evet

Özet

AIM: Adrenomedullin (ADM) is a potent vasodilator peptide. ADM and nitric oxide (NO) are produced in vascular endothelial cells. Increased ADM level has been linked to hyperdynamic circulation and arterial vasodilatation in cirrhotic portal hypertension (CPH). The role of ADM in non-cirrhotic portal hypertension (NCPH) is unknown. plasma ADM levels were studied in patients with NCPH, compensated and decompensated cirrhosis in order to determine its contribution to portal hypertension (PH) in these groups.