Adrenomedullin in cirrhotic and non-cirrhotic portal hypertension


TAHAN V., AVŞAR E., KARACA C., Uslu E., EREN F., Aydin S., ...More

WORLD JOURNAL OF GASTROENTEROLOGY, vol.9, no.10, pp.2325-2327, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 9 Issue: 10
  • Publication Date: 2003
  • Doi Number: 10.3748/wjg.v9.i10.2325
  • Journal Name: WORLD JOURNAL OF GASTROENTEROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2325-2327
  • Istanbul University Affiliated: Yes

Abstract

AIM: Adrenomedullin (ADM) is a potent vasodilator peptide. ADM and nitric oxide (NO) are produced in vascular endothelial cells. Increased ADM level has been linked to hyperdynamic circulation and arterial vasodilatation in cirrhotic portal hypertension (CPH). The role of ADM in non-cirrhotic portal hypertension (NCPH) is unknown. plasma ADM levels were studied in patients with NCPH, compensated and decompensated cirrhosis in order to determine its contribution to portal hypertension (PH) in these groups.