Serum Angiopoietin-like peptide 4 levels in patients with hepatic steatosis

Altun O., Dikker O., Arman Y., Ugurlukisi B., Kutlu O., Cil E. O., ...Daha Fazla

CYTOKINE, cilt.111, ss.496-499, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 111
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.cyto.2018.05.030
  • Dergi Adı: CYTOKINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.496-499
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objectives: Angiopoietin-like peptide 4 (ANGPTL-4) plays an important role in lipid metabolism by inhibiting the enzyme lipoprotein lipase. This effect of ANGPTL-4 results in suppression of the release of plasma triglyceri-dederived fatty acids. Increase in fatty acid levels entering to the liver and abnormalities in their secretion is one of the main mechanisms in pathogenesis of hepatic steatosis. In this study, we aimed to investigate the role of ANGPTL-4 in pathogenesis of hepatic steatosis by determining its levels in patients with fatty liver disease.