The association of serous tubal intraepithelial carcinoma with gynecologic pathologies and its role in pelvic serous cancer

Koc N., Ayas S., UYGUR L.

GYNECOLOGIC ONCOLOGY, vol.134, no.3, pp.486-491, 2014 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 134 Issue: 3
  • Publication Date: 2014
  • Doi Number: 10.1016/j.ygyno.2014.07.089
  • Journal Name: GYNECOLOGIC ONCOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.486-491
  • Keywords: Pelvic serous cancer, Tuba, Precursor, Ovarian cancer, FALLOPIAN-TUBE, OVARIAN-CANCER, TP53 MUTATIONS, GRADE, DIAGNOSIS, ADENOCARCINOMA, PATHOGENESIS, FREQUENCY, PRECURSOR, PATTERNS
  • Istanbul University Affiliated: No

Abstract

Objectives. Possible primary sites of pelvic serous cancers are, fallopian tubes, ovaries or peritoneum. Recent studies have revealed that a portion of these tumors originates from serous tubal intraepithelial carcinoma (STIC) at the distal end of fallopian tubes. In this study, the association of STIC with pelvic serous carcinomas and the pathologic parameters that indicate the tubes as the primary site were assessed.