Within-subject and between-subject biological variation estimates of 21 hematological parameters in 30 healthy subjects

COSKUN A., Carobene A., KILERCIK M., SERTESER M., Sandberg S., Aarsand A. K., ...More

CLINICAL CHEMISTRY AND LABORATORY MEDICINE, vol.56, no.8, pp.1309-1318, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 56 Issue: 8
  • Publication Date: 2018
  • Doi Number: 10.1515/cclm-2017-1155
  • Journal Name: CLINICAL CHEMISTRY AND LABORATORY MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1309-1318
  • Keywords: biological variation, complete blood count, hematology, preanalytical phase, REFERENCE CHANGE VALUES, CLINICAL-CHEMISTRY, EUROPEAN FEDERATION, LABORATORY MEDICINE, CRITICAL-APPRAISAL, SAMPLES, CHECKLIST, REVEALS, PROJECT, SERUM
  • Istanbul University Affiliated: No

Abstract

Background: The complete blood count (CBC) is used to evaluate health status in the contexts of various clinical situations such as anemia, infection, inflammation, trauma, malignancies, etc. To ensure safe clinical application of the CBC, reliable biological variation (BV) data are required. The study aim was to define the BVs of CBC parameters employing a strict protocol.